Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ab Hōʻike Kiʻi Hōʻike

Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ab Mea Ho'āʻo

Huahana Huahana:RC-CF31

Mea inoa: Canine Heartworm Ag/Anaplasma Ab /Ehrlichia canis Ab/Leishmania Ab pahu ho'āʻo

Helu helu: RC-CF31

Ka hōʻuluʻulu manaʻo: ʻike ʻia o Canine Dirofilaria immitis antigens, Anaplasma antibodies, E. canis antibodies a me LSH antibodies i loko o 10 mau minuke.

Kumu: Hoʻokahi ʻanuʻu immunochromatographic assay

ʻIke ʻia nā pahuhopu:

CHW Ag : Dirofilaria immitis antigens Anapalsma Ab : Anaplasma antibodies

E. canis Ab : E. canis antibodies

LSH Ab : L. chagasi, L. infantum, a me L. donovani

nā mea pale

Laʻana: Canine Whole Blood, Plasma or Serum

Ka manawa heluhelu: 10 ~ 15 minuke

Waihona: lumi wela (ma 2 ~ 30 ℃)

Hoʻopau: 24 mau mahina ma hope o ka hana ʻana

E hoʻouna i ka leka uila iā mākou KĀLĀKĀ

Huahana Huahana

CHW Ag/Anaplasma Ab/E.canis Ab/LSH Ab pahu ho'āʻo Canine Heartworm Ag/Anaplasma Ab /Ehrlichia canis Ab/Leishmania Ab pahu ho'āʻo

Helu helu	RC-CF31
Hōʻuluʻulu manaʻo	Ka ʻike ʻana o Canine Dirofilaria immitis antigens, Anaplasma antibodies, E. canis antibodies a me LSH antibodies i loko o 10 mau minuke.
Kumukānāwai	Hoʻokahi ʻanuʻu immunochromatographic assay
Nā Huhu ʻIke	CHW Ag : Dirofilaria immitis antigens Anapalsma Ab : Anaplasma antibodiesE. canis Ab : E. canis antibodies LSH Ab : L. chagasi, L. infantum, a me L. donovani nā mea pale
Laʻana	ʻO ke koko holoʻokoʻa ʻo Canine, Plasma a i ʻole Serum
Heluhelu manawa	10 minuke

Ka nui	1 pahu (kit) = 10 mau mea hana (Paʻi kanaka)
ʻIkepili	ʻO ka pahu hoʻāʻo, ka ʻōmole Buffer, a me ka mea hoʻoheheʻe hoʻopau
Waihona	Ka Mahana lumi (ma 2 ~ 30 ℃)
Hoʻopau	24 mahina ma hope o ka hana ʻana
E akahele	E hoʻohana i loko o 10 mau minuke ma hope o ka wehe ʻanaE hoʻohana i ka nui kūpono o ka laʻana (0.01 ml o kahi dropper) E hoʻohana ma hope o 15 ~ 30 mau minuke ma RT inā mālama ʻia lākou ma lalo o ke anuanu E noʻonoʻo i ka hopena o ka hoʻāʻo ʻana ma hope o 10 mau minuke

ʻIkepili

Hoʻonui ka ʻiʻo puʻuwai makua i mau ʻīniha ka lōʻihi a noho i loko o nā aʻaʻa pulmonary kahi e loaʻa ai ka nui o nā meaʻai. ʻO ka ʻiʻo puʻuwai i loko o ke aʻa e hoʻoulu ai i ka mumū a hana i ka hematoma. A laila, pono ka puʻuwai e pāpaʻi pinepine ma mua o ka wā ma mua i ka piʻi ʻana o nā ʻiʻo puʻuwai i ka nui, e ālai ana i nā aʻa.

Ke emi mai ka maʻi (ʻoi aku ma mua o 25 mau ʻīlio puʻuwai i loko o ka ʻīlio 18 kg), neʻe ka puʻuwai i ka atrium ʻākau, e pale ana i ke kahe o ke koko.

Ke piʻi ka helu o nā ʻuʻu puʻuwai ma mua o 50, hiki iā lākou ke noho

nā atrium a me nā ventricles.

Ke loaʻa i ka maʻi ʻoi aku ma mua o 100 heartworms ma ka ʻāpana ʻākau o ka puʻuwai, nalowale ka ʻīlio i ka hana o ka puʻuwai a make. ʻO kēia mea make

Ua kapa ʻia ʻo "Caval Syndrom."

ʻAʻole e like me nā parasite ʻē aʻe, waiho ka puʻuwai i nā inike liʻiliʻi i kapa ʻia he microfilaria. Neʻe ka microfilaria i loko o ka ʻīlio i ka wā e omo ai ka makika i ke koko mai ka ʻīlio. ʻO nā ʻiʻo puʻuwai hiki ke ola i loko o ka mea hoʻokipa no 2 mau makahiki e make inā ʻaʻole lākou e neʻe i kahi hoʻokipa ʻē aʻe i loko o ia manawa. Hiki i nā parasite e noho ana i loko o ka ʻīlio hāpai ke hoʻopōʻino i kāna ʻōpuʻu.

He mea koʻikoʻi ka nānā mua ʻana i nā ʻiʻo puʻuwai i ka hoʻopau ʻana iā lākou. Hele nā ʻanuʻu puʻuwai e like me L1, L2, L3 me ka pae hoʻoili ma o ka makika a lilo i ʻiʻo puʻuwai makua.

Puuwai i ka makika

ʻO ka microfilaria i loko o ka makika e ulu aʻe i L2 a me L3 parasite hiki ke hoʻopili i nā ʻīlio i nā pule he nui. Pili ka ulu ʻana i ka lewa. ʻO ka mahana maikaʻi no ka parasite ma luna o 13.9 ℃.

Ke nahu ka makika i ka ʻīlio, komo ka microfilaria o L3 i loko o kona ʻili. Ma ka ʻili, ulu ka microfilaria i L4 no 1-2 pule. Ma hope o ka noho ʻana i ka ʻili no 3 mau mahina, ulu ka L4 i L5, e neʻe ana i loko o ke koko.

L5 e like me ke ʻano o ka heartworm makua e komo i loko o ka puʻuwai a me nā aʻa pulmonary kahi 5-7 mau mahina ma hope e waiho ai nā naʻau i nā inike.

ʻIkepili

Pono e noʻonoʻo ʻia ka mōʻaukala maʻi a me ka ʻikepili lapaʻau o kahi ʻīlio maʻi, a me nā ʻano diagnostic like ʻole i ka ʻike ʻana i ka ʻīlio. No ka laʻana, X-ray, ultrasound scan, hoʻokolokolo koko, ʻike i ka microfilaria a, i ka hihia ʻino loa, pono ke autopsy.

Ka nānā 'ana i ka serum;

Ka ʻike ʻana o nā antibodies a i ʻole nā antigens i loko o ke koko

ʻO ka hoʻokolokolo antigen;

Hoʻopili kēia i ka ʻike ʻana i nā antigens kikoʻī o nā puʻuwai makua wahine. Hoʻokō ʻia ka hoʻokolokolo ma ka haukapila a kiʻekiʻe kona helu kūleʻa. Hoʻolālā ʻia nā pahu hoʻāʻo i loaʻa ma ka mākeke no ka ʻike ʻana i nā puʻuwai makua makua 7 ~ 8 mahina i paʻakikī ke ʻike ʻia nā puʻuwai ʻōpio ma mua o 5 mau mahina.

Lapaʻau

Hoʻōla maikaʻi ʻia ka maʻi o ka ʻiʻo puʻuwai i ka nui o nā hihia. No ka hoʻopau ʻana i nā ʻōpū puʻuwai a pau, ʻo ka hoʻohana ʻana i nā lāʻau lapaʻau ke ala maikaʻi loa. ʻO ka ʻike mua ʻana i nā ʻiʻo naʻau e hoʻonui i ka holomua o ka mālama ʻana. Eia nō naʻe, i ka wā hope o ka maʻi, hiki ke hoʻopiʻi ʻia, ʻoi aku ka paʻakikī o ka mālama ʻana.

ʻIkepili

Hiki i ka ma'i ma'i Anaplasma phagocytophilum (Ehrilichia phagocytophila ma mua) ke ho'oulu i ka ma'i i kekahi mau holoholona me ke kanaka. ʻO ka maʻi i loko o nā ruminants home ua kapa ʻia hoʻi ʻo tick-borne fever (TBF), a ua ʻike ʻia no ka liʻiliʻi he 200 mau makahiki. ʻO nā maʻi bacteria o ka ʻohana Anaplasmataceae he gram-negative, nonmotile, coccoid a ellipsoid organisms, ʻokoʻa ka nui mai 0.2 a 2.0um anawaena. He aerobes obligate lākou, nele i ke ala glycolytic, a he mau parasites intracellular obligate. Noho nā ʻano ʻano āpau i loko o ka genus Anaplasma i nā vacuoles i hoʻopaʻa ʻia me ka membrane i loko o nā pūnaeho hematopoietic ʻoi ʻole a oʻo paha o ka host mammalian. Hoʻopili ka phagocytophilum i nā neutrophils a ʻo ka huaʻōlelo granulocytotropic e pili ana i nā neutrophils maʻi. ʻAʻole loaʻa nā mea ola i loko o nā eosinophils.

Anaplasma phagocytophilum

Nā hōʻailona

Nā hōʻailona lapaʻau maʻamau oʻO ka anaplasmosis canine e pili ana i ke kuni kiʻekiʻe, ka lethargy, ke kaumaha a me ka polyarthritis. Hiki ke ʻike ʻia nā hōʻailona neurologic (ataxia, hopu a me ka ʻeha ʻāʻī). ʻO ka maʻi Anaplasma phagocytophilum ʻaʻole hiki ke make ke ʻole ka paʻakikī e nā maʻi ʻē aʻe. Ua ʻike ʻia nā poho pololei, nā kūlana ʻōʻopa a me nā poho hana i nā keiki hipa. Ua hoʻopaʻa ʻia ka hoʻopaʻa ʻana a me ka spermatogenesis maikaʻi ʻole i nā hipa a me nā pipi. Hoʻopili ʻia ka paʻakikī o ka maʻi e kekahi mau kumu, e like me nā ʻano like ʻole o Anaplasma phagocytophilum i pili, nā pathogens ʻē aʻe, ka makahiki, ke kūlana immune a me ke kūlana o ka mea hoʻokipa, a me nā mea e like me ke aniau a me ka hoʻokele. Pono e ʻōlelo ʻia ʻo nā hōʻike lapaʻau i loko o ke kanaka mai kahi maʻi maʻi like ʻole e like me ka maʻi, a i kahi maʻi hoʻoweliweli. Eia nō naʻe, ʻo ka hapa nui o nā maʻi maʻi kanaka e hopena i ka liʻiliʻi a i ʻole nā hōʻike lapaʻau.

Hoʻouna ʻia

Hoʻouna ʻia ʻo Anaplasma phagocytophilum e nā ticks ixodid. Ma ʻAmelika Hui Pū ʻIa, ʻo Ixodes scapularis a me Ixodes pacificus nā vectors nui, ʻoiai ʻo Ixode ricinus i ʻike ʻia ʻo ia ka vector exophilic nui ma ʻEulopa. Hoʻouna ʻia ʻo Anaplasma phagocytophilum e kēia mau kiʻi vector, a ʻaʻohe hōʻike o ka transovarial transmission. ʻO ka hapa nui o nā haʻawina a hiki i kēia lā i noiʻi i ke koʻikoʻi o nā pūʻali mammalian o A. phagocytophilum a me kāna mau mea hoʻokalakupua i kālele i nā rodents akā aia kēia ʻano mea i ka laulā o nā mea hoʻokipa mammalian, e hoʻopili ana i nā pōpoki hānai, nā ʻīlio, nā hipa, nā bipi, a me nā lio.

ʻIkepili

ʻO ka indirect immunofluorescence assay ka hoʻāʻo nui i hoʻohana ʻia e ʻike i ka maʻi. Hiki ke loiloi ʻia nā laʻana serum acute a convalescent no ka huli ʻana i kahi hoʻololi ʻehā o ka titer antibody i Anaplasma phagocytophilum. ʻIke ʻia nā mea hoʻokomo intracellular (morulea) i loko o nā granulocytes ma Wright a i ʻole Gimsa stained blood smears. Hoʻohana ʻia nā ʻano hana polymerase chain reaction (PCR) e ʻike i ka DNA Anaplasma phagocytophilum.

Kāohi

ʻAʻohe lāʻau lapaʻau no ka pale ʻana i ka maʻi Anaplasma phagocytophilum. Hoʻopili ʻia ka pale ʻana i ka ʻike ʻole ʻana i ka vector tick (Ixodes scapularis, Ixodes pacificus, a me Ixode ricinus) mai ka pūnāwai a hiki i ka hāʻule ʻana, ka hoʻohana prophylatic o nā antiacaricides, a me ka hoʻohana prophylactic o doxycycline a i ʻole tetracycline i ke kipa ʻana iā Ixodes scapularis, Ixodes pacificus, a me Ixode ricinus tick.

ʻIkepili

ʻO Ehrlichia canis he ʻano liʻiliʻi liʻiliʻi a me ke ʻano koʻokoʻo i lawe ʻia e ka ʻīlio ʻīlio ʻeleʻele, Rhipicephalus sanguineus. ʻO E. canis ke kumu o ka ehrlichiosis maʻamau i nā ʻīlio. Hiki i nā ʻīlio ke maʻi e kekahi mau Ehrlichia spp. akā ʻo ka mea maʻamau e hoʻoulu ai i ka ehrlichiosis canine ʻo E. canis.

Ua ʻike ʻia ua laha ʻo E. canis ma ʻAmelika Hui Pū ʻIa, ʻEulopa, ʻAmelika Hema, ʻAsia a me ke Kaiwaenahonua.

Hiki i nā ʻīlio maʻi i mālama ʻole ʻia ke lilo i mea lawe asymptomatic o ka maʻi no nā makahiki a make i ka hemorrhage nui.

Nā hōʻailona

Hoʻokaʻawale ʻia ka maʻi Ehrlichia canis i nā ʻīlio i 3 mau pae;

ACUTE PHASE: He ʻano haʻahaʻa loa kēia. ʻAʻole papa inoa ka ʻīlio, ʻaʻohe meaʻai, a ua hoʻonui ʻia paha nā pūpū lymph. Loaʻa paha ke kuni akā ʻaʻole hiki i kēia māhele ke pepehi i ka ʻīlio. Hoʻomaʻemaʻe ka hapa nui o ke kino iā lākou iho akā e hele kekahi i ka pae aʻe.

SUBCLINICAL PHASE: Ma kēia māhele, ʻike ʻia ka ʻīlio maʻamau. Ua hoʻopaʻa ʻia ke kino i loko o ka spleen a peʻe maoli i laila.

KA PALAPALA MA'I: Ma keia mahele, ma'i hou ka ilio. Ma kahi o 60% o nā ʻīlio i loaʻa i ka maʻi E. canis e loaʻa i ke koko ʻokoʻa ma muli o ka emi ʻana o ka helu platelets. ʻO ka ʻeha hohonu i loko o nā maka i kapa ʻia ʻo "uveitis" hiki ke loaʻa ma muli o ka hoʻoulu ʻana i ka immune no ka wā lōʻihi. Hiki ke ʻike ʻia nā hopena neurologic.

ʻIke a me ka mālama ʻana

Pono ka hōʻoia ʻana o Ehrlichia canis i ka nānā ʻana i ka morula i loko o nā monocytes ma ka cytology, ka ʻike ʻana o E. canis serum antibodies me ka indirect immunofluorescence antibody test (IFA), polymerase chain reaction (PCR) amplification, a/a i ʻole gel blotting (Western immunoblotting).

ʻO ke kumu nui o ka pale ʻana i ka ehrlichiosis canine ʻo ia ka mālama ʻana i ka tick. ʻO ka lāʻau lapaʻau i koho ʻia no ka mālama ʻana no nā ʻano ehrlichiosis a pau he doxycycline no hoʻokahi mahina. Pono e hoʻomaikaʻi nui ʻia i loko o 24-48 mau hola ma hope o ka hoʻomaka ʻana o ka mālama ʻana i nā ʻīlio me ka maʻi acute-phase a i ʻole ka maʻi maʻi maʻi. I loko o kēia manawa, hoʻomaka ka piʻi ʻana o ka helu platelet a pono e maʻamau i loko o 14 mau lā ma hope o ka hoʻomaka ʻana o ka mālama ʻana.

Ma hope o ka maʻi, hiki ke lilo hou i ka maʻi; ʻaʻole mau ka palekana ma hope o ka maʻi ma mua.

Kāohi

ʻO ka pale maikaʻi loa o ka ehrlichiosis ʻo ka mālama ʻana i nā ʻīlio me ka ʻole o nā ticks. Pono e hoʻokomo i ka nānā ʻana i ka ʻili i kēlā me kēia lā no ka maʻi a me ka mālama ʻana i nā ʻīlio me ka mālama ʻana i ka tick. No ka lawe ʻana i nā maʻi ʻino ʻē aʻe, e like me ka maʻi Lyme, anaplasmosis a me Rocky Mountain spotted fever, he mea nui ka mālama ʻana i nā ʻīlio ʻole.

ʻIkepili

ʻO ka Leishmaniasis kahi maʻi parasitic nui a koʻikoʻi o nā kānaka, nā ʻīlio a me nā ʻīlio. ʻO ka lāʻau o leishmaniasis he protozoan parasite a no ka leishmania donovani complex. Hoʻolaha nui ʻia kēia parasite ma nā ʻāina wela a me nā subtropical o ʻEulopa Hema, ʻApelika, ʻAsia, ʻAmelika Hema a me Central America. ʻO Leishmania donovani infantum (L. infantum) ke kuleana o ka maʻi manu a me nā ʻīlio ma ʻEulopa Hema, ʻApelika, a me ʻAsia. ʻO Canine Leishmaniasis kahi maʻi ʻōnaehana holomua koʻikoʻi. ʻAʻole nā ʻīlio a pau e hoʻomohala i ka maʻi maʻi ma hope o ka inoculation me nā parasites. ʻO ka ulu ʻana o ka maʻi maʻi e pili ana i ke ʻano o ka pane ʻana i ka pale ʻana i loaʻa i kēlā me kēia holoholona

kū'ē i nā parasites.

Nā hōʻailona

I ka Canine

Hiki ke loaʻa nā hōʻike visceral a me nā ʻili i ka manawa like i nā ʻīlio; ʻAʻole like me ke kanaka, ʻaʻole ʻike ʻia nā maʻi maʻi ʻokoʻa a me visceral. He ʻokoʻa nā hōʻailona lapaʻau a hiki ke hoʻohālike i nā maʻi ʻē aʻe. Hiki pū kekahi maʻi asymptomatic. Hiki i nā hōʻailona visceral maʻamau ke komo i ke kuni (hiki ke hoʻopau ʻia), anemia, lymphadenopathy, splenomegaly, lethargy, hoʻemi i ka hoʻomanawanui hoʻoikaika kino, pohō kaumaha, a me ka emi ʻana o ka ʻai. ʻO nā hōʻailona visceral liʻiliʻi e pili ana i ka maʻi maʻi, ka luaʻi, melena, glomerulonephritis, hāʻule ʻole o ka ate, epistaxis, polyuria-polydipsia, sneezing, lameness (no ka polyarthritis a i ʻole myositis), ascites, a me ka colitis mau loa.

I ka Feline

Kakaʻikahi ka maʻi o nā pōpoki. I ka hapa nui o nā pōpoki i hoʻopaʻa ʻia, ua kaupalena ʻia nā ʻeha i nā maʻi ʻeha ʻili, ʻike pinepine ʻia ma nā lehelehe, ka ihu, ka lihilihi a i ʻole ka pinnae. He kakaikahi na ma'i visceral a me na hoailona.

Po'ai ola

Hoʻopau ʻia ka pōʻai ola i ʻelua mau pūʻali. He pūʻali vertebrate a me kahi pūʻali ʻāʻī (sand fly). ʻAi ka lele one wahine i ka mea hoʻokipa vertebrate ahoʻokomo i nā amastigotes. Hoʻokumu ʻia nā promastigotes flagellated i loko o ka inike. Hoʻokomo ʻia nā promastigotes i loko o ka pūʻali vertebrate i ka wā e hānai ai i ka nalo. Hoʻokumu nā promastigotes i amastigotes a hoʻonui nui i loko o nā macrophages. ʻO ka hoʻonui ʻana i loko o nā macrophages o ka ʻili, mucosa a me viscera, ke kumu o ka leishmaniasis cutaneous, mucosal a me visceral leishmaniasis.

ʻIkepili

I nā ʻīlio, ʻike pinepine ʻia ka leishmaniasis ma o ka nānā pono ʻana i nā parasites, me ka hoʻohana ʻana iā Giemsa a i ʻole nā ʻili wikiwiki, i nā hamo mai ka lymph node, spleen, a i ʻole ka iwi iwi aspirates, tissue biopsies, a i ʻole nā ʻili ʻili mai nā ʻeha. Hiki ke loaʻa nā mea ola i loko o nā maʻi ocular, ʻoi aku hoʻi i nā granulomas. He poepoe na amastigotes a i ka oval parasites, me ka poepoe basophilic nucleus a me ka rodlike kinetoplast. Loaʻa iā lākou i loko o nā macrophages a i ʻole i hoʻokuʻu ʻia mai nā cell ruptured. Hoʻohana pū ʻia nā ʻenehana immunohistochemistry a me ka polymerase chain reaction (PCR).

Kāohi

ʻO nā lāʻau i hoʻohana pinepine ʻia ʻo ia: Meglumine Antimoniate pili me Allopurinol, Aminosidine, a me Amphotericin B. ʻO kēia mau lāʻau āpau e koi i ka regimen nui, a pili kēia i ke kūlana o ka mea maʻi a me ka hui pū ʻana o ka mea nona. Manaʻo ʻia e mālama ʻia ka mālama ʻana me ka allopurinol, no ka mea, ʻaʻole hiki ke hōʻoia ʻaʻole e hoʻi hou nā ʻīlio inā hoʻopau ʻia ka mālama ʻana. Pono e hoʻohana mau ʻia ka hoʻohana ʻana i nā kola i loaʻa i nā insecticides, shampoos a i ʻole nā sprays no ka pale ʻana i nā ʻīlio mai ka nahu ʻana o ka sandfly no nā maʻi āpau e mālama ʻia. ʻO ka mana vector kekahi o nā mea koʻikoʻi o ka mālama ʻana i nā maʻi.

Pilikia ka nalo one i nā lāʻau lāʻau e like me ka maʻi malaria.

Mua: Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab Testst Kit

Aʻe: ʻO Lifecosm Canine Lyme Ab Test Kit

E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou